Defending champions Asante Kotoko have been drawn against Division One outfit Future Stars in the Round of 64 of the MTN FA Cup.
Two-time titleholders Medeama SC will come up against Rospak FC, while historic side Sekondi Eleven Wise have been handed a tough test against Premier League leaders FC Samartex 1996.
Record champions Hearts of Oak will meet third-tier True Life FC, as Na God FC and Dreams FC prepare for clashes with Accra Great Olympics and Semper FI, respectively.
All fixtures are scheduled for the weekend of November 25–27, 2025.
Full Fixtures
