It was also a first loss for Carlo Ancelotti’s side in 36 matches in all competitions – dating back to 18 January against Atletico Madrid in the Copa del Rey.

Jonathan David scored the only goal from the penalty spot for Lille after a video assistant referee (VAR) review ruled that Real’s French midfielder Eduardo Camavinga had blocked Edon Zhegrova’s free-kick with his arm.

The hosts were superb throughout and more than merited their victory to get up and running in this season’s competition following a 2-0 loss to Sporting in their opening game.

Prior to scoring from the spot, Canada international David was denied by a superb double save from visiting keeper Andriy Lunin as Bruno Genesio’s team dominated proceedings.

However, they were forced to hang on at the end against a Real side that introduced Kylian Mbappe – returning from a thigh injury – just before the hour mark.

A late rally from the visitors saw Antonio Rudiger’s header cleared off the line and Arda Guler head a gilt-edged opportunity straight at home goalkeeper Lucas Chevalier.

Real, who beat Stuttgart in their opening match, host Borussia Dortmund in a repeat of last term’s final in their next Champions League fixture, while Lille travel to Atletico Madrid.

The Blues have asked for conditions on signing the forwards, having attempted a swap deal to sign Aston Villa’s Jhon Duran and seeing a £34m bid rejected for Atletico Madrid’s Samu Omorodion.

They remain keen to sign a striker after talks with Enzo Maresca in Marbella following his appointment as manager earlier this month.

David, 24, who is currently playing in the Copa America with Canada, has been subject to early talks and would cost less than £30m as he enters the last year of his deal at Lille.

But Manchester United, Tottenham and West Ham are also believed to be interested.

Chelsea are also interested in Guiu, 18, whose deal at Barcelona expires next summer and has a £5m active release clause in it.

Guiu, who has scored twice in six appearances for Barcelona, is also in talks to renew his deal with the Catalan giants.

Chelsea still want to sign a winger after seeing primary target Michael Olise opt to join Bayern Munich amid a disagreement over wage demands and his squad role.

Meanwhile, the Blues agreed a £37.5m deal for defender Ian Maatsen to join Aston Villa, with midfielder Omari Kellyman set to move in the opposite direction for £19m in a separate deal.